Vitamin K2 (Menaquinone)｜HerbBB ingredient encyclopedia

Why supplement?

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Supports osteocalcin activation and bone maintenance

K2 takes part in osteocalcin carboxylation, helping direct calcium toward bone use, and is a common part of bone-nutrition strategies.

Clinical evidence: Moderate

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Supports pathways involved in regulating vascular calcification

K2 is involved in activating vitamin K-dependent proteins such as MGP and is linked to calcification-regulation pathways; real-world clinical benefit still depends on the form and the population.

Research evidence: Preliminary to moderate

How to take it

With foodTake with a meal that contains fat for better absorption

Best timeAnytime

MK-4 and MK-7 differ in half-life and research data, so check the product form.

General wellnessThere is no separate adult K2 recommended intake; total vitamin K AI is 120 mcg/day for men and 90 mcg/day for women.

Specific needsDoses for bone or clotting use should be set by a clinician according to the condition.

How oftenDo not self-start high doses without a medical need; people on anticoagulants should ask a doctor first.

What to watch

Cautions

Anyone taking warfarin or other anticoagulants must ask a doctor first.

Do not replace prescribed osteoporosis treatment with vitamin K2 on your own.

Common side effects

· Usual supplement doses are generally well tolerated

Rare but important

· May interfere with anticoagulation control.

Long-term dependenceDoes not cause addiction or typical tolerance.