01
Why supplement?
✓
MK-4 support for bone metabolism
Helps maintain osteocalcin activation and bone-metabolism balance.
Clinical evidence: Moderate✓
Involved in activating clotting proteins
Like other vitamin K forms, K2 takes part in activating vitamin K–dependent clotting proteins.
Mechanism: EstablishedADVERTISEMENT
02
How to take it
With foodTake with a meal that contains fat for better absorption
Best timeAnytime
May be taken in divided doses as needed.
General wellnessThere is no separate adult K2 recommended intake; total vitamin K AI is 120 mcg/day for men and 90 mcg/day for women.
Specific needsDoses for bone or clotting use should be set by a clinician according to the condition.
How oftenDo not self-start high doses without a medical need; people on anticoagulants should ask a doctor first.
03
What to watch
Cautions
Anyone taking warfarin or other anticoagulants must ask a doctor first.
Do not replace prescribed osteoporosis treatment with vitamin K2 on your own.
Common side effects
· Usual supplement doses are generally well tolerated
Rare but important
· May interfere with anticoagulation control.
Long-term dependenceDoes not cause addiction or typical tolerance.