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Herb · in-depth review

St. John's Wort

St. John's Wort

May help with day-to-day management of mild low mood.

Also known asSt. John's WortHypericum perforatum

Key benefit

May help with day-to-day management of mild low mood.

Clinical evidence: Moderate

Functional support

Helps, alongside diet and lifestyle, maintain everyday physical function.

Use context: Common
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With foodMost can be taken with meals; if the gut is sensitive, take after food.
Best timePrefer morning or daytime; avoid evening use if it affects sleep.

After 4-8 weeks of continuous use, review actual benefit and tolerance.

General wellnessFollow the labeled dose, and start on the low side.
Specific needsIf you have a specific health goal or medical history, have a clinician adjust use to your situation.

How oftenGenerally can be used daily and adjusted to individual response.

Cautions

It has notable interactions with many medicines and must not be combined with antidepressants on your own.

If symptoms persist or worsen, seek medical help promptly.

Common side effects

· Mild gastrointestinal discomfort or an unfamiliar taste may occur.

Rare but important

· Some people may have allergic reactions or interactions with medicines.

Long-term dependenceNo typical addiction evidence; do not self-use high long-term doses just to speed results.

Medical disclaimerThis page is compiled by the HerbBB editorial team for general health information only. It is not a substitute for advice from a doctor, pharmacist, or other qualified clinician. If you have a health condition, take medicines, or are pregnant or breastfeeding, speak with a professional first.